Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168642 | 0.83 | SLC6A4 (0.53) | SLC6A4HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL20168641 | 0.83 | SLC6A4 (0.53) | SLC6A4HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL26490602 | 0.78 | PSEN1 (0.59) | PLGPRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL5806608 | 0.77 | SLC6A4 (0.54) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL26073693 | 0.76 | SLC6A4 (0.53) | SLC6A4HDAC3HDAC4HDAC1HDAC6 | |
| SCHEMBL26073698 | 0.75 | KMT2A (0.61) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL20182251 | 0.75 | TRPV1 (0.47) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL20168527 | 0.75 | TRPV1 (0.47) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL20168529 | 0.75 | TRPV1 (0.47) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL9787693 | 0.74 | MMP1 (0.55) | SLC6A4TDP1CAPN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220218839-A1 | SELECTIVE UV CROSSLINKING OF PEPTIDES AND FUNCTIONAL MOIETIES TO IMMUNOGLOBULINS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2022-07-14 | — | — | US | disclosed |
| US-11116848-B2 | Selective UV crosslinking of peptides and functional moieties to immunoglobulins | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-09-14 | — | — | US | disclosed |
| EP-2970440-B1 | SELECTIVE UV CROSSLINKING OF PEPTIDES AND FUNCTIONAL MOIETIES TO IMMUNOGLOBULINS | UNIV NOTRE DAME DU LAC (US) | 2019-11-20 | — | — | EP | disclosed |
| US-20190328896-A1 | SELECTIVE UV CROSSLINKING OF PEPTIDES AND FUNCTIONAL MOIETIES TO IMMUNOGLOBULINS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2019-10-31 | — | — | US | disclosed |
| US-20160022834-A1 | SELECTIVE UV CROSSLINKING OF PEPTIDES AND FUNCTIONAL MOIETIES TO IMMUNOGLOBULINS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2016-01-28 | — | — | US | disclosed |