Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.47 |
| ▸ | SPR | P35270 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168527 | 1.00 | TRPV1 (0.47) | TRPV1SPRCA12CA1CA2 | |
| SCHEMBL20168529 | 1.00 | TRPV1 (0.47) | TRPV1SPRCA12CA1CA2 | |
| SCHEMBL20168642 | 0.91 | SLC6A4 (0.53) | CA12CA1CA2CA9SLC6A4 | |
| SCHEMBL20168641 | 0.91 | SLC6A4 (0.53) | CA12CA1CA2CA9SLC6A4 | |
| SCHEMBL30109374 | 0.83 | SPR (0.47) | TRPV1SPRCA12CA1CA2 | |
| SCHEMBL5806608 | 0.80 | SLC6A4 (0.54) | CA12CA1CA2CA9SLC6A4 | |
| SCHEMBL9787693 | 0.79 | MMP1 (0.55) | SLC6A4CAPN1TDP1 | |
| SCHEMBL26073693 | 0.79 | SLC6A4 (0.53) | CA12CA1CA2CA9SLC6A4 | |
| SCHEMBL20182419 | 0.78 | TRPV1 (0.70) | TRPV1SPRFAAHPTGS2KDM4E | |
| SCHEMBL21470293 | 0.78 | TRPV1 (0.70) | TRPV1SPRFAAHPTGS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352326-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2019-10-17 | — | — | US | disclosed |
| WO-2018094005-A1 | MYELOPEROXIDASE IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | MPO, CAT, EPX | TRPV1 3731/4885SPR 242/4885CA12 936/4885 |
| US-11352326-B2 | Myeloperoxidase imaging agents | MPO, CAT, EPX | TRPV1 3731/4885SPR 242/4885CA12 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.