Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5364 | 0.89 | MAPT (0.49) | TSHRALOX15MAPK1MAPTALDH1A1 | |
| SCHEMBL880077 | 0.83 | ALDH1A1 (0.41) | TSHRMAPK1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL13553943 | 0.79 | MAPT (0.46) | TSHRALOX15MAPK1MAPTALDH1A1 | |
| SCHEMBL1665962 | 0.79 | PDK1 (0.49) | TSHRALOX15MAPK1MAPTALDH1A1 | |
| Ethylene SCHEMBL4705578 | 0.74 | ALDH1A1 (0.49) | TSHRALOX15MAPK1MAPTALDH1A1 | |
| SCHEMBL5483 | 0.73 | ALDH1A1 (0.51) | TSHRALOX15MAPK1MAPTALDH1A1 | |
| SCHEMBL2375356 | 0.72 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4221 | 0.72 | — | — | |
| SCHEMBL8891623 | 0.72 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL237380 | 0.72 | MAPT (0.60) | MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249180-B2 | C-3 alkyl and alkenyl modified betulinic acid derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-02-02 | — | — | US | disclosed |