SCHEMBL17468960

SCHEMBL17468960

CCC[C@H](C)CC(=O)NCC#N

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTSK P43235 9/20 0.41
CTSS P25774 9/20 0.41
MCL1 Q07820 3/20 0.40
CTSL P07711 3/20 0.37
TSHR P16473 1/20 0.35
GGPS1 O95749 2/20 0.33
FDPS P14324 2/20 0.33
CTSB P07858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7449899 0.81 GGPS1 (0.36) CTSKCTSSMCL1CTSLGGPS1
SCHEMBL1707139 0.78 SMN1; SMN2 (0.43) CTSKCTSSMCL1CTSLCTSB
SCHEMBL23798946 0.74 PSMB5 (0.36) TSHRGGPS1FDPS
SCHEMBL14518701 0.74 GGPS1 (0.38) MCL1TSHRGGPS1FDPS
SCHEMBL21603664 0.74 TSHR (0.42) MCL1TSHR
SCHEMBL14672993 0.73 CTSS (0.50) CTSKCTSSCTSLTSHRCTSB
SCHEMBL17468956 0.73 ALDH1A1 (0.56) TSHRGGPS1FDPS
SCHEMBL9321698 0.73 CASP2 (0.56)
SCHEMBL27000234 0.73 ECE1 (0.45) GGPS1FDPS
SCHEMBL13799021 0.72 TSHR (0.41) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016012362-A1 SUBSTITUTED CYANO CYCLOALKYL PENTA-2,4-DIENES, CYANO CYCLOALKYL PENT-2-EN-4-YNES, CYANO HETEROCYCLYL PENTA-2,4-DIENES AND CYANO HETEROCYCLYL PENT-2-EN-4-YNES AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-01-28 WO disclosed