Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 8/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469074 | 0.83 | KDM4E (0.33) | MAOBSMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL17469010 | 0.82 | GUSB (0.35) | — | |
| SCHEMBL17459442 | 0.78 | GUSB (0.37) | MAOBLTA4HMAPT | |
| SCHEMBL17469075 | 0.72 | GUSB (0.35) | — | |
| SCHEMBL17468768 | 0.69 | FFAR1 (0.35) | KDM1A | |
| SCHEMBL17468781 | 0.69 | GUSB (0.36) | MAOBLTA4HMAPT | |
| SCHEMBL11048736 | 0.62 | ESR1 (0.54) | MAOBGAAALDH1A1 | |
| SCHEMBL29393223 | 0.61 | LTA4H (0.60) | LTA4H | |
| SCHEMBL17468760 | 0.61 | LDHA (0.35) | — | |
| SCHEMBL5211220 | 0.60 | TAAR1 (0.59) | MAOBTSHRPKMHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |