Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1124286 | 0.82 | TGM2 (0.52) | LMNASCN9ATNKSPARP1TNKS2 | |
| SCHEMBL1313357 | 0.82 | LMNA (0.52) | LMNASCN9ATNKSPARP1TNKS2 | |
| SCHEMBL13701947 | 0.81 | L3MBTL1 (0.62) | LMNATNKSPARP1TNKS2MAPK1 | |
| SCHEMBL3094168 | 0.80 | KDM4E (0.50) | LMNASCN9AMAPK1PIK3CDPIK3CA | |
| SCHEMBL1032919 | 0.80 | NOTUM (0.53) | LMNASCN9AMAPK1KMT2AKDM4E | |
| SCHEMBL17864343 | 0.80 | NOTUM (0.53) | LMNASCN9ATNKSPARP1TNKS2 | |
| SCHEMBL14617665 | 0.79 | PPID (0.63) | LMNASCN9ATNKSPARP1TNKS2 | |
| SCHEMBL23545613 | 0.77 | KDM4E (0.51) | LMNASCN9APARP1MAPK1KMT2A | |
| SCHEMBL21426081 | 0.77 | LMNA (0.45) | LMNASCN9ATNKSPARP1TNKS2 | |
| SCHEMBL14508050 | 0.77 | KLKB1 (0.56) | LMNASCN9ATNKSPARP1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |