Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469387 | 0.84 | RAB9A (0.45) | RAB9ANPC1POLBCYP1A2CYP2C19 | |
| SCHEMBL17469415 | 0.81 | RAB9A (0.42) | RAB9ANPC1POLBCYP1A2CYP2C19 | |
| SCHEMBL17459521 | 0.72 | BCL2L1 (0.46) | RAB9AMAPTSMN1; SMN2CHATALDH1A1 | |
| SCHEMBL17459520 | 0.72 | BCL2L1 (0.46) | RAB9AMAPTSMN1; SMN2CHATALDH1A1 | |
| SCHEMBL28675354 | 0.72 | CYP1A1 (0.48) | CYP1A2CYP2C19HSD17B10KDM4EMAPT | |
| SCHEMBL17469388 | 0.72 | POLB (0.46) | RAB9ANPC1POLBCYP1A2ADORA3 | |
| SCHEMBL17469313 | 0.71 | TTR (0.42) | RAB9AMAPTSMN1; SMN2CHATALDH1A1 | |
| SCHEMBL16191542 | 0.71 | MAPT (0.57) | RAB9ANPC1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL16191921 | 0.71 | MAOA (0.63) | RAB9ANPC1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL30358578 | 0.71 | MAPT (0.57) | RAB9ANPC1CYP1A2CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016013976-A1 | METHOD OF FORMING A MULTI-SUBSTITUTED BENZENE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-01-28 | — | — | WO | disclosed |