Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | BAD | Q92934 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459520 | 0.86 | BCL2L1 (0.46) | RAB9AMAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL17459521 | 0.86 | BCL2L1 (0.46) | RAB9AMAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL17469313 | 0.85 | TTR (0.42) | RAB9AMAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL17469389 | 0.84 | RAB9A (0.43) | RAB9ANPC1POLBCYP1A2CYP2C19 | |
| SCHEMBL16307435 | 0.84 | CYP3A4 (0.52) | RAB9ANPC1POLBCYP1A2CYP2C19 | |
| SCHEMBL17469415 | 0.83 | RAB9A (0.42) | RAB9ANPC1POLBCYP1A2CYP2C19 | |
| SCHEMBL17469388 | 0.81 | POLB (0.46) | RAB9ANPC1POLBCYP1A2KDM4E | |
| SCHEMBL17459513 | 0.81 | TRPA1 (0.49) | RAB9ANPC1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL17459512 | 0.81 | TRPA1 (0.49) | RAB9ANPC1CYP1A2CYP2C19HSD17B10 | |
| SCHEMBL17469335 | 0.80 | TRPA1 (0.48) | CYP1A2CYP2C19HSD17B10KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016013976-A1 | METHOD OF FORMING A MULTI-SUBSTITUTED BENZENE COMPOUND | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-01-28 | — | — | WO | disclosed |