Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | TTK | P33981 | 2/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 5/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 5/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16129387 | 0.91 | FGFR4 (0.45) | HTR1DTRPM8SLC6A4TTKCARM1 | |
| SCHEMBL16129386 | 0.90 | MTNR1A (0.43) | HTR1DTRPM8SLC6A4TTKCARM1 | |
| SCHEMBL16129426 | 0.89 | FGFR4 (0.49) | TTKCARM1PRMT1NTRK1KDM4E | |
| SCHEMBL20066384 | 0.88 | PRMT1 (0.43) | HTR1DTRPM8SLC6A4CARM1PRMT1 | |
| SCHEMBL17469493 | 0.88 | APP (0.38) | HTR1DTRPM8SLC6A4TTKCARM1 | |
| SCHEMBL17469455 | 0.88 | CARM1 (0.39) | HTR1DTRPM8SLC6A4TTKCARM1 | |
| SCHEMBL16119991 | 0.87 | TRPM8 (0.48) | HTR1DTRPM8SLC6A4TTKCARM1 | |
| SCHEMBL17469454 | 0.87 | MAOB (0.41) | CARM1PRMT1MAOB | |
| SCHEMBL16129388 | 0.87 | MAOB (0.43) | CARM1PRMT1ACHEMAOB | |
| SCHEMBL16129429 | 0.87 | FGFR4 (0.48) | TTKNTRK1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160024017-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024017-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | PRMT1, PRMT3, PRMT5 | HTR1D 4435/4885TRPM8 4468/4885SLC6A4 2069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.