Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.41 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21158005 | 0.97 | ESR1 (0.44) | ESR1ESR2MAPK1HTTHDAC1 | |
| SCHEMBL17470440 | 0.97 | ESR1 (0.44) | ESR1ESR2MAPK1HTTHDAC1 | |
| SCHEMBL17470577 | 0.96 | ESR1 (0.44) | ESR1ESR2MAPK1HTTHDAC1 | |
| SCHEMBL17470561 | 0.94 | ESR1 (0.42) | ESR1ESR2MAPK1HTTHDAC1 | |
| SCHEMBL19193719 | 0.94 | ESR1 (0.44) | ESR1ESR2MAPK1HTTHDAC1 | |
| SCHEMBL17470480 | 0.94 | ESR1 (0.44) | ESR1ESR2MAPK1HTTHDAC1 | |
| SCHEMBL17470629 | 0.94 | ESR1 (0.46) | ESR1ESR2MAPK1HTTHDAC1 | |
| SCHEMBL19193792 | 0.94 | ESR1 (0.44) | ESR1ESR2MAPK1HTTHDAC1 | |
| SCHEMBL18999372 | 0.94 | ESR1 (0.46) | ESR1ESR2MAPK1HTTHDAC1 | |
| SCHEMBL20776017 | 0.93 | ESR1 (0.45) | ESR1ESR2MAPK1HTTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172775-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2022-04-20 | — | — | EP | disclosed |
| US-20170222157-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-08-03 | — | — | US | disclosed |
| US-20170222157-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-08-03 | — | — | US | disclosed |
| WO-2016012075-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170222157-A1 | MATERIALS FOR ELECTRONIC DEVICES | EYA3, EYA2, MITF | ESR1 12/4885ESR2 90/4885MAPK1 2385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.