SCHEMBL1747131

SCHEMBL1747131

COc1ccc(-c2cc3cc(CCC(=O)O)ccc3o2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 10/20 0.73
MAOA P21397 2/20 0.60
KDM4E B2RXH2 3/20 0.56
MAPT P10636 3/20 0.56
ALDH1A1 P00352 2/20 0.56
PKM P14618 1/20 0.56
MAOB P27338 1/20 0.56
APP P05067 3/20 0.52
PTGES O14684 1/20 0.51
ALOX5 P09917 1/20 0.51
CYP2C8 P10632 1/20 0.49
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
LMNA P02545 1/20 0.48
TP53 P04637 1/20 0.48
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A3 Q01959 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1744659 0.89 MAOA (0.62) FFAR1MAOAKDM4EMAPTALDH1A1
SCHEMBL1745020 0.87 FFAR1 (0.77) FFAR1MAOAMAOB
SCHEMBL19166583 0.86 FFAR1 (0.78) FFAR1KDM4EALDH1A1MAOBCYP1A2
SCHEMBL3013456 0.86 CYP2C8 (0.68) FFAR1MAOAKDM4EMAPTALDH1A1
SCHEMBL3012615 0.84 FFAR1 (0.63) FFAR1KDM4EMAPTPTGESALOX5
SCHEMBL29214227 0.82 MAOA (0.61) FFAR1MAOAKDM4EMAPTALDH1A1
SCHEMBL30861765 0.82 MAOA (0.61) FFAR1MAOAKDM4EMAPTALDH1A1
SCHEMBL19137125 0.82 FFAR1 (1.00) FFAR1MAOAMAOB
SCHEMBL17667824 0.81 FFAR1 (0.60) FFAR1KDM4EMAPTCYP2C8CYP3A4
SCHEMBL17518897 0.81 FFAR1 (1.00) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1559422-B1 RECEPTOR FUNCTION CONTROLLING AGENT TAKEDA PHARMACEUTICAL (JP) 2014-04-30 EP disclosed
EP-2385032-A1 GPR40 Receptor function regulator Takeda Pharmaceutical Company Limited (JP) 2011-11-09 EP disclosed
US-7960369-B2 Receptor function regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-14 US disclosed
US-20090012093-A1 Receptor Function Regulator TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-01-08 US disclosed
EP-1559422-A1 RECEPTOR FUNCTION CONTROLLING AGENT Takeda Pharmaceutical Company Limited (JP) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012093-A1 Receptor Function Regulator GPR119, GIPR, INSR FFAR1 33/4885MAOA 4245/4885KDM4E 3200/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.