Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 3/20 | 0.43 |
| ▸ | F3 | P13726 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17474641 | 1.00 | MAPT (0.50) | MAPTALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL27365510 | 0.92 | ALDH1A1 (0.43) | MAPTALDH1A1CYP19A1OXER1PPARG | |
| Crotonic Acid SCHEMBL28077513 | 0.80 | MAPT (0.52) | MAPTALDH1A1CYP19A1OXER1PPARG | |
| Butadiene SCHEMBL16290288 | 0.79 | TSHR (0.44) | MAPTALDH1A1CYP19A1OXER1PPARG | |
| Butadiene SCHEMBL16290286 | 0.79 | TSHR (0.44) | MAPTALDH1A1CYP19A1OXER1PPARG | |
| SCHEMBL31609 | 0.78 | — | — | |
| SCHEMBL115342 | 0.78 | — | — | |
| SCHEMBL193238 | 0.78 | — | — | |
| SCHEMBL5077461 | 0.78 | — | — | |
| SCHEMBL19358959 | 0.77 | TSHR (0.57) | MAPTALDH1A1CYP19A1OXER1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791342-B1 | MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME | BRASKEM SA (BR) | 2020-04-29 | — | — | EP | disclosed |
| US-10273505-B2 | Modified microorganisms and methods of making butadiene using same | BRASKEM S.A. (BR) | 2019-04-30 | — | — | US | disclosed |
| US-20180346936-A1 | MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME | BRASKEM S.A. (BR) | 2018-12-06 | — | — | US | disclosed |
| US-10059963-B2 | Modified microorganisms and methods of making butadiene using same | BRASKEM S.A. (BR) | 2018-08-28 | — | — | US | disclosed |
| US-20160032325-A1 | MODIFIED MICROORGANISMS AND METHODS OF MAKING BUTADIENE USING SAME | BRASKEM S.A. (BR) | 2016-02-04 | — | — | US | disclosed |