Crotonic Acid

Crotonic Acid

SCHEMBL28077513

C=CCCC(=O)O.CC=CC(=O)O

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.52
ABCC4 O15439 1/20 0.52
ALDH1A1 P00352 4/20 0.37
LMNA P02545 3/20 0.37
FFAR1 O14842 1/20 0.35
CYP19A1 P11511 1/20 0.35
RXRA P19793 1/20 0.35
PPARG P37231 1/20 0.35
OXER1 Q8TDS5 1/20 0.35
TSHR P16473 4/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
BLM P54132 1/20 0.32
SLC6A3 Q01959 1/20 0.32
MEN1 O00255 1/20 0.32
CYP2D6 P10635 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
FFAR3 O14843 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Crotonic Acid SCHEMBL11525007 0.83 ALOX15 (0.36) MAPTABCC4ALDH1A1LMNATSHR
Crotonic Acid SCHEMBL2406680 0.83 ALOX15 (0.36) MAPTABCC4ALDH1A1LMNATSHR
Crotonic Acid SCHEMBL1618932 0.83 ALOX15 (0.36) MAPTABCC4ALDH1A1LMNATSHR
Succinic Acid SCHEMBL28205145 0.82 EGLN1 (0.50) LMNATSHRBLMNFKB1FFAR3
Succinic Acid SCHEMBL28100381 0.82 EGLN1 (0.50) LMNATSHRBLMNFKB1FFAR3
SCHEMBL115342 0.82
Crotonic Acid SCHEMBL11237082 0.81 ABCC4 (0.39) MAPTABCC4ALDH1A1LMNATSHR
SCHEMBL17474641 0.80 MAPT (0.50) MAPTABCC4ALDH1A1LMNAFFAR1
SCHEMBL17474642 0.80 MAPT (0.50) MAPTABCC4ALDH1A1LMNAFFAR1
Acetic Acid SCHEMBL16598390 0.80 MAPT (0.56) MAPTABCC4ALDH1A1LMNAFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106604975-A Binder for adhesives for floor-coverings 巴斯夫欧洲公司 2017-04-26 CN disclosed
CN-106536572-A METHOD FOR PRODUCING FREEZE-THAW STABLE, AQUEOUS DISPERSIONS 巴斯夫欧洲公司 2017-03-22 CN disclosed
CN-106459297-A Process for preparing aqueous polymer dispersions 巴斯夫欧洲公司 2017-02-22 CN disclosed
CN-103459442-B As the scale inhibition additive washed with cleaning product and the copolymer comprising hydroxy-acid group, sulfo group and polyalkylene oxide groups 巴斯夫欧洲公司 2016-08-10 CN disclosed
CN-105793409-A Bactericidal cleaning composition for hard surfaces 艺康美国股份有限公司 2016-07-20 CN disclosed
CN-105765047-A Alkaline detergent compositions containing carboxylic acid terpolymers for hard water scale control 艺康美国股份有限公司 2016-07-13 CN disclosed