SCHEMBL1747686

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1747688	1.00	PKM (0.34)	PKMCYP3A4CYP2D6SLC6A2SLC6A4
	SCHEMBL1747689	1.00	PKM (0.34)	PKMCYP3A4CYP2D6SLC6A2SLC6A4
	SCHEMBL1747740	0.89	CASP6 (0.33)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL1747741	0.89	CASP6 (0.33)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL1747742	0.89	CASP6 (0.33)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL3254592	0.88	SMN1; SMN2 (0.36)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL3254596	0.88	SMN1; SMN2 (0.36)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL3254588	0.88	SMN1; SMN2 (0.36)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL1747818	0.86	SMN1; SMN2 (0.37)	PKMCYP3A4CYP2D6SLC6A2SLC6A4
	SCHEMBL1747816	0.86	SMN1; SMN2 (0.37)	PKMCYP3A4CYP2D6SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.