Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949995 | 0.97 | DHODH (0.39) | DHODHMEN1KMT2ALMNA | |
| SCHEMBL14698541 | 0.91 | DHODH (0.41) | DHODHMEN1KMT2ALMNANTRK1 | |
| SCHEMBL12911779 | 0.91 | DHODH (0.38) | DHODHMEN1KMT2ALMNA | |
| SCHEMBL10028784 | 0.90 | DHODH (0.41) | DHODHMEN1KMT2ALMNANTRK1 | |
| SCHEMBL951388 | 0.89 | DHODH (0.40) | DHODHMEN1KMT2ALMNANTRK1 | |
| SCHEMBL13072418 | 0.89 | DHODH (0.38) | DHODHMEN1KMT2ALMNANTRK1 | |
| SCHEMBL12528079 | 0.88 | DHODH (0.39) | DHODHMEN1KMT2ALMNA | |
| SCHEMBL17750084 | 0.88 | DHODH (0.39) | DHODHMEN1KMT2ALMNANTRK1 | |
| SCHEMBL15741755 | 0.88 | DHODH (0.40) | DHODHMEN1KMT2ALMNANTRK1 | |
| SCHEMBL120823 | 0.88 | DHODH (0.39) | DHODHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2967063-B1 | LAWN GROWTH-PROMOTING AGENT AND METHOD OF USING SAME | BAYER CROPSCIENCE AG (DE) | 2017-10-18 | — | — | EP | disclosed |
| US-20160029629-A1 | LAWN GROWTH-PROMOTING AGENT AND METHOD OF USING SAME | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160029629-A1 | LAWN GROWTH-PROMOTING AGENT AND METHOD OF USING SAME | FGF2, FGF1, MKI67 | DHODH 542/4885MEN1 835/4885KMT2A 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.