SCHEMBL12911779

SCHEMBL12911779

CC(=O)NN(C)C(=O)c1cc(Br)cc(Br)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.38
▸ MALT1 Q9UDY8 4/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14698541 0.93 DHODH (0.41) DHODHMALT1MEN1KMT2ALMNA
SCHEMBL13072418 0.93 DHODH (0.38) DHODHMEN1KMT2ALMNA
SCHEMBL31438694 0.92 DHODH (0.39) DHODHMALT1MEN1KMT2A
SCHEMBL120823 0.92 DHODH (0.39) DHODHMALT1MEN1KMT2A
SCHEMBL14960688 0.92 DHODH (0.37) DHODHMEN1KMT2ALMNA
SCHEMBL949995 0.92 DHODH (0.39) DHODHMALT1MEN1KMT2ALMNA
Acetic Acid SCHEMBL17477064 0.91 DHODH (0.38) DHODHMEN1KMT2ALMNA
SCHEMBL10028784 0.91 DHODH (0.41) DHODHMALT1MEN1KMT2ALMNA
SCHEMBL951388 0.90 DHODH (0.40) DHODHMALT1MEN1KMT2ALMNA
SCHEMBL12528079 0.89 DHODH (0.39) DHODHMALT1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7867949-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-11 — — US disclosed
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090181956-A1 Hydrazide Compound and Pesticidal Use of the Same ACHE, DDT, CAT DHODH 284/4885MALT1 4865/4885MEN1 1803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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