Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575703 | 0.90 | CA1 (0.61) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL42732 | 0.88 | CA1 (0.64) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL28108955 | 0.86 | CA1 (0.61) | MAPTHPGDALDH1A1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL8359634 | 0.86 | CA1 (0.61) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL6935338 | 0.83 | CA1 (0.77) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL20591202 | 0.83 | TDP1 (0.77) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL5887658 | 0.83 | TSHR (0.67) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL929744 | 0.83 | MAPT (0.57) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL14937438 | 0.82 | MAPT (0.50) | MAPTHPGDALDH1A1KDM4ELMNA | |
| SCHEMBL7908252 | 0.82 | CA1 (0.57) | MAPTHPGDALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180307-B1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | SEEGPHARM SA (CH) | 2019-02-13 | — | — | EP | disclosed |
| US-9845289-B2 | Process for the synthesis of Dapsone and its intermediates | SEEGPHARM SA (CH) | 2017-12-19 | — | — | US | disclosed |
| US-20170217883-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | SEEGPHARM SA (CH) | 2017-08-03 | — | — | US | disclosed |
| EP-3180307-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | Seegpharm SA (CH) | 2017-06-21 | — | — | EP | disclosed |
| WO-2016016321-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | SEEGPHARM SA (CH) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217883-A1 | PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES | DHPS, FDPS, DAP3 | MAPT 3725/4885HPGD 59/4885ALDH1A1 1853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.