Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599835 | 0.92 | TSHR (0.45) | TSHRCYP2C19CYP3A4ALDH1A1TP53 | |
| Phosphoric Acid SCHEMBL17477137 | 0.84 | LPAR3 (0.38) | CYP2C19LMNAFDPS | |
| SCHEMBL5908907 | 0.82 | TSHR (0.65) | TSHRCYP2C19CYP3A4TP53TDP1 | |
| SCHEMBL2472181 | 0.81 | ALDH1A1 (0.37) | TSHRCYP2C19LMNAFDPSGRM4 | |
| SCHEMBL2470417 | 0.81 | LPAR3 (0.39) | CYP2C19LMNAFDPSTDP1 | |
| SCHEMBL3628446 | 0.81 | CYP2C19 (0.36) | TSHRCYP2C19TP53TDP1 | |
| SCHEMBL9264971 | 0.79 | CYP2C19 (0.35) | CYP2C19LMNAFDPSGRM4TP53 | |
| SCHEMBL6840461 | 0.79 | SAT1 (0.35) | CYP2C19LMNAFDPSGRM4TP53 | |
| SCHEMBL2782188 | 0.79 | TP53 (0.36) | CYP2C19LMNAFDPSGRM4TP53 | |
| Ammonia Solution, Strong SCHEMBL27519730 | 0.79 | LPAR3 (0.38) | CYP2C19LMNAFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016851-A1 | MELT POLYMERIZED POLYCARBONATE | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-02-04 | — | — | WO | disclosed |