SCHEMBL17477708

SCHEMBL17477708

O=Cc1ccc(COCc2ccc(O)cc2)o1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
TSHR P16473 1/20 0.51
ALOX5 P09917 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
TP53 P04637 1/20 0.36
MDM2 Q00987 1/20 0.36
DAO P14920 1/20 0.36
IDO1 P14902 2/20 0.36
HTR2B P41595 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278333 0.86 ALDH1A1 (0.61) ALDH1A1TSHRTP53MDM2MEN1
SCHEMBL22289462 0.85 TSHR (0.50) ALDH1A1TSHRALOX5TP53MDM2
SCHEMBL19248450 0.83 POLB (0.52) ALDH1A1TSHRMEN1KMT2APOLB
SCHEMBL17693406 0.79 ALDH1A1 (0.57) ALDH1A1TSHRTP53MDM2MEN1
SCHEMBL10374139 0.77 ALDH1A1 (0.50) ALDH1A1TSHRALOX5ESR2TP53
SCHEMBL4299568 0.77 ALDH1A1 (0.59) ALDH1A1TSHRTP53MDM2POLB
SCHEMBL273028 0.76 ALDH1A1 (0.53) ALDH1A1TSHRALOX5TP53MDM2
SCHEMBL4301950 0.74 ALDH1A1 (0.56) ALDH1A1TSHRTP53MDM2POLB
SCHEMBL18066379 0.74 ALDH1A1 (0.56) ALDH1A1TSHRTP53MDM2MEN1
SCHEMBL17867344 0.74 ALDH1A1 (0.71) ALDH1A1TSHRTP53MDM2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016017840-A1 PAIN RELIEVING OR THERAPEUTIC AGENT CONTAINING GASTRODIA ELATA EXTRACT 안국약품 주식회사 2016-02-04 WO claimed
WO-2016017840-A1 PAIN RELIEVING OR THERAPEUTIC AGENT CONTAINING GASTRODIA ELATA EXTRACT 안국약품 주식회사 2016-02-04 WO disclosed
WO-2016017840-A1 PAIN RELIEVING OR THERAPEUTIC AGENT CONTAINING GASTRODIA ELATA EXTRACT 안국약품 주식회사 2016-02-04 WO disclosed