SCHEMBL1747771

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27478228	0.82	NAPRT (0.46)	KMT2ASMN1; SMN2RAB9ANAPRTCYP3A4
	SCHEMBL31420077	0.81	NAPRT (0.48)	SMN1; SMN2NAPRTLMNA
	SCHEMBL1747676	0.81	NAPRT (0.48)	SMN1; SMN2NAPRTLMNA
	SCHEMBL13235872	0.81	NAPRT (0.44)	KMT2ASMN1; SMN2RAB9ANAPRTCYP3A4
	SCHEMBL1747714	0.80	CYP3A4 (0.39)	FFAR2SMN1; SMN2RAB9ANAPRTCYP3A4
	SCHEMBL12844720	0.80	FFAR2 (0.39)	FFAR2KMT2ASMN1; SMN2RAB9AMAPT
	SCHEMBL1747739	0.80	POLB (0.43)	KMT2ASMN1; SMN2RAB9ANAPRTMAPT
	SCHEMBL26986367	0.78	L3MBTL1 (0.56)	FFAR2SMN1; SMN2RAB9AMAPTNPC1
	SCHEMBL26955949	0.77	FFAR2 (0.68)	FFAR2SLC6A4SLC6A3
	SCHEMBL12844797	0.76	CYP3A4 (0.35)	FFAR2KMT2ASMN1; SMN2RAB9ANAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.