Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.38 |
| ▸ | FDPS | P14324 | 9/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16541722 | 0.80 | CES2 (0.42) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL5806390 | 0.75 | FDPS (0.43) | TSHRTHRBCES2GGPS1FDPS | |
| SCHEMBL8922491 | 0.74 | TSHR (0.35) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL23700072 | 0.74 | TSHR (0.42) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL23700088 | 0.74 | TSHR (0.42) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL23700067 | 0.74 | TSHR (0.42) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL16672477 | 0.74 | TSHR (0.42) | TSHRTHRBCES2LPAR1LPAR3 | |
| SCHEMBL11866694 | 0.73 | FDPS (0.42) | CES2LPAR1LPAR3GGPS1FDPS | |
| SCHEMBL5455594 | 0.73 | FDPS (0.42) | CES2LPAR1LPAR3GGPS1FDPS | |
| SCHEMBL1016952 | 0.73 | FDPS (0.42) | CES2LPAR1LPAR3GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016018148-A1 | BIOSENSOR COMPRISING A MODIFIED METAL SURFACE AND METHOD FOR THE MODIFICATION OF A METAL SURFACE | BIOMARQUE B.V. (NL) | 2016-02-04 | — | — | WO | disclosed |