Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.39 |
| ▸ | LPL | P06858 | 7/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | F11 | P03951 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748048 | 1.00 | P4HB (0.41) | P4HBLIPGLPLCA1CA2 | |
| SCHEMBL1747986 | 1.00 | P4HB (0.41) | P4HBLIPGLPLCA1CA2 | |
| SCHEMBL1748045 | 0.79 | ALDH1A1 (0.38) | PDE4D | |
| SCHEMBL1748043 | 0.79 | ALDH1A1 (0.38) | PDE4D | |
| SCHEMBL1748044 | 0.79 | ALDH1A1 (0.38) | PDE4D | |
| SCHEMBL180740 | 0.75 | DGAT1 (0.45) | P4HBLIPGLPLCA1CA2 | |
| SCHEMBL2311893 | 0.75 | NPC1 (0.35) | CA1CA2CA9CA12CA14 | |
| SCHEMBL2635172 | 0.75 | DGAT1 (0.45) | P4HBLIPGLPLCA1CA2 | |
| SCHEMBL2635174 | 0.75 | DGAT1 (0.45) | P4HBLIPGLPLCA1CA2 | |
| SCHEMBL2635176 | 0.75 | DGAT1 (0.45) | P4HBLIPGLPLCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8013166-B2 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER HEALTHCARE LLC (US) | 2011-09-06 | — | — | US | disclosed |