Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 3/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17482111 | 0.95 | TSHR (0.34) | TSHRABL1RIN1HDAC8 | |
| SCHEMBL16156488 | 0.92 | DHODH (0.32) | TSHRDHODHHDAC8 | |
| SCHEMBL17482109 | 0.90 | ABL1 (0.33) | DHODHABL1RIN1 | |
| SCHEMBL18355981 | 0.89 | TSHR (0.31) | TSHRABL1RIN1 | |
| SCHEMBL18356137 | 0.85 | DHODH (0.31) | DHODH | |
| SCHEMBL16156489 | 0.85 | MLYCD (0.39) | TSHRDHODHHDAC8 | |
| SCHEMBL17482096 | 0.85 | HTT (0.38) | TSHR | |
| SCHEMBL17482103 | 0.84 | ABL1 (0.35) | ABL1RIN1 | |
| SCHEMBL1767050 | 0.81 | ABL1 (0.33) | ABL1RIN1HDAC8 | |
| SCHEMBL18355982 | 0.81 | ABL1 (0.33) | ABL1RIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9402395-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-02 | — | — | US | disclosed |
| US-20160029623-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160029623-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | TSHR 3230/4885DHODH 2125/4885ABL1 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.