Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17482103 | 0.94 | ABL1 (0.35) | ABL1RIN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL1767050 | 0.91 | ABL1 (0.33) | ABL1RIN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL17482097 | 0.90 | TSHR (0.32) | ABL1RIN1DHODH | |
| SCHEMBL17482150 | 0.85 | SMN1; SMN2 (0.31) | KMT2AGPBAR1 | |
| SCHEMBL17482147 | 0.85 | GPBAR1 (0.40) | GPBAR1 | |
| SCHEMBL17482098 | 0.84 | GPBAR1 (0.41) | KMT2AGPBAR1 | |
| SCHEMBL17482111 | 0.84 | TSHR (0.34) | ABL1RIN1KMT2AALDH1A1 | |
| SCHEMBL15228222 | 0.83 | ALDH1A1 (0.34) | ABL1RIN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1766938 | 0.82 | GAA (0.39) | KMT2AGPBAR1DHODHALDH1A1TAS1R3 | |
| SCHEMBL1766977 | 0.82 | NR1H3 (0.38) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9402395-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-02 | — | — | US | disclosed |
| US-20160029623-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160029623-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | ABL1 1530/4885RIN1 760/4885KMT2A 2126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.