Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 5/20 | 0.37 |
| ▸ | BRAF | P15056 | 5/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17482112 | 0.96 | HTT (0.41) | HTTCYP2C19GFERNPSR1TSHR | |
| SCHEMBL17482096 | 0.92 | HTT (0.38) | HTTCYP2C19GFERNPSR1TSHR | |
| SCHEMBL17482159 | 0.91 | MLYCD (0.40) | NPSR1TSHRBRAFRXFP1TRPV4 | |
| SCHEMBL17482101 | 0.90 | GPBAR1 (0.42) | CSF1RBRAFRXFP1L3MBTL1 | |
| SCHEMBL17482099 | 0.88 | HTT (0.41) | HTTCYP2C19GFERNPSR1TSHR | |
| SCHEMBL17482158 | 0.87 | MLYCD (0.42) | TSHRRXFP1KDM4EALDH1A1TRPV4 | |
| SCHEMBL17482152 | 0.84 | MLYCD (0.39) | TSHRRXFP1KDM4EALDH1A1TRPV4 | |
| SCHEMBL16156489 | 0.83 | MLYCD (0.39) | TSHRRXFP1KDM4EALDH1A1TRPV4 | |
| SCHEMBL18355894 | 0.82 | HTT (0.36) | HTTCYP2C19GFERNPSR1TSHR | |
| SCHEMBL17482098 | 0.82 | GPBAR1 (0.41) | TSHRCSF1RBRAFRXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9402395-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-02 | — | — | US | disclosed |
| US-9402395-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-02 | — | — | US | disclosed |
| US-20160029623-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | US | disclosed |
| US-20160029623-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160029623-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | HTT 2019/4885CYP2C19 581/4885GFER 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.