Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 5/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17482159 | 0.96 | MLYCD (0.40) | MLYCDTYK2RXFP1DHODHJAK2 | |
| SCHEMBL17482152 | 0.95 | MLYCD (0.39) | MLYCDTYK2RXFP1DHODHJAK2 | |
| SCHEMBL16156489 | 0.94 | MLYCD (0.39) | MLYCDTYK2RXFP1DHODHJAK2 | |
| SCHEMBL17482112 | 0.91 | HTT (0.41) | MLYCDRXFP1TSHR | |
| SCHEMBL17482156 | 0.91 | DHODH (0.37) | MLYCDDHODH | |
| SCHEMBL17484781 | 0.90 | MLYCD (0.42) | MLYCDTYK2RXFP1TSHRGPBAR1 | |
| SCHEMBL17482148 | 0.90 | MLYCD (0.42) | MLYCDTYK2RXFP1TSHRTRPV4 | |
| SCHEMBL17482153 | 0.88 | GPBAR1 (0.43) | MLYCDTYK2RXFP1JAK2JAK1 | |
| SCHEMBL17482107 | 0.87 | HTT (0.39) | RXFP1TSHRKDM4EALDH1A1TRPV4 | |
| SCHEMBL17484742 | 0.86 | MLYCD (0.38) | MLYCDTYK2RXFP1DHODHJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975845-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-22 | — | — | US | disclosed |
| US-9975845-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2018-05-22 | — | — | US | disclosed |
| US-20170152214-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-01 | — | — | US | disclosed |
| US-20170152214-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-06-01 | — | — | US | disclosed |
| US-9635853-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-02 | — | — | US | disclosed |
| US-9635853-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-02 | — | — | US | disclosed |
| US-20160029624-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | US | disclosed |
| US-20160029624-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152214-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | MLYCD 1777/4885TYK2 4800/4885RXFP1 3170/4885 |
| US-20160029624-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | MLYCD 1777/4885TYK2 4800/4885RXFP1 3170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.