SCHEMBL17482901

SCHEMBL17482901

c1ccc2c(c1)Oc1cc(-c3cccc4oc5ccccc5c34)ccc1C21c2ccccc2Oc2cc(-c3cccc4oc5cnccc5c34)ccc21

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.32
TDO2 P48775 3/20 0.30
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17483019 0.98 IDO1 (0.31) TDO2IDO1
SCHEMBL17482881 0.94 TNF (0.32) IDO1
SCHEMBL17482894 0.94 ALOX5 (0.32) ALOX5TDO2
SCHEMBL17483022 0.91 TNF (0.32) ALOX5
SCHEMBL17483018 0.91 PDK2 (0.36)
SCHEMBL17482899 0.90 ALOX5 (0.37) ALOX5
SCHEMBL17482874 0.86 PDK2 (0.38) ALOX5
SCHEMBL17482873 0.85 PLA2G2A (0.37) ALOX5
SCHEMBL17482903 0.84 KDM4E (0.39) ALOX5
SCHEMBL17482915 0.82 ALOX5 (0.42) ALOX5TDO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160035986-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-02-04 US disclosed
US-20160035986-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160035986-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNT1, CCNA1 ALOX5 2408/4885TDO2 3453/4885IDO1 3216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.