Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483160 | 0.85 | KDM4E (0.57) | KDM4EMAPTL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL1102250 | 0.85 | KDM4E (0.57) | KDM4EMAPTL3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL29002814 | 0.83 | KDM4E (0.63) | TDP1KDM4ERAB9AMAPTL3MBTL1 | |
| SCHEMBL29540705 | 0.80 | KDM4E (0.71) | TDP1KDM4ERAB9AMAPTL3MBTL1 | |
| SCHEMBL151122 | 0.80 | KDM4E (0.71) | TDP1KDM4ERAB9AMAPTL3MBTL1 | |
| SCHEMBL28098262 | 0.78 | RORA (0.50) | KDM4EALDH1A1HTTPOLBPKM | |
| SCHEMBL29002887 | 0.76 | KDM4E (0.63) | TDP1KDM4ERAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL29351992 | 0.76 | SMN1; SMN2 (0.43) | KDM4ERAB9ADHODHMAPTALDH1A1 | |
| SCHEMBL17483153 | 0.76 | SMN1; SMN2 (0.43) | KDM4ERAB9ADHODHMAPTALDH1A1 | |
| SCHEMBL23845876 | 0.75 | GPR3 (0.48) | TDP1KDM4ERAB9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844087-B2 | Method of suppressing formation of photocrosslink, and photoreactive nucleic acid in which auto-crosslink formation is suppressed | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2020-11-24 | — | — | US | disclosed |
| US-10450334-B2 | Photoresponsive nucleotide analogue having photocrosslinking ability | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2019-10-22 | — | — | US | disclosed |
| US-20160326207-A1 | METHOD OF SUPPRESSING FORMATION OF PHOTOCROSSLINK, AND PHOTOREACTIVE NUCLEIC ACID IN WHICH AUTO-CROSSLINK FORMATION IS SUPPRESSED | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-11-10 | — | — | US | disclosed |
| US-20160326207-A1 | METHOD OF SUPPRESSING FORMATION OF PHOTOCROSSLINK, AND PHOTOREACTIVE NUCLEIC ACID IN WHICH AUTO-CROSSLINK FORMATION IS SUPPRESSED | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-11-10 | — | — | US | disclosed |
| US-20160031918-A1 | PHOTORESPONSIVE NUCLEOTIDE ANALOGUE HAVING PHOTOCROSSLINKING ABILITY | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2016-02-04 | — | — | US | disclosed |
| US-20160031918-A1 | PHOTORESPONSIVE NUCLEOTIDE ANALOGUE HAVING PHOTOCROSSLINKING ABILITY | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450334-B2 | Photoresponsive nucleotide analogue having photocrosslinking ability | PCNA, DPYD, NUDT1 | TDP1 150/4885KDM4E 3068/4885RAB9A 2289/4885 |
| US-20160326207-A1 | METHOD OF SUPPRESSING FORMATION OF PHOTOCROSSLINK, AND PHOTOREACTIVE NUCLEIC ACID IN WHICH AUTO-CROSSLINK FORMATION IS SUPPRESSED | PCNA, POLL, LIG1 | TDP1 182/4885KDM4E 4084/4885RAB9A 3980/4885 |
| US-10844087-B2 | Method of suppressing formation of photocrosslink, and photoreactive nucleic acid in which auto-crosslink formation is suppressed | UPP1, UNG, PCNA | TDP1 57/4885KDM4E 4000/4885RAB9A 4003/4885 |
| US-20160031918-A1 | PHOTORESPONSIVE NUCLEOTIDE ANALOGUE HAVING PHOTOCROSSLINKING ABILITY | PCNA, DPYD, NUDT1 | TDP1 150/4885KDM4E 3068/4885RAB9A 2289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.