SCHEMBL17483433

SCHEMBL17483433

c1cncc(-c2nc(-c3ccc(-n4c5ccccc5c5cc(-c6ccc7[nH]c8ccccc8c7c6)ccc54)cc3)nc(-c3cccnc3)n2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 3/20 0.42
TLR7 Q9NYK1 3/20 0.42
TLR9 Q9NR96 2/20 0.42
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
TDO2 P48775 1/20 0.39
NPY5R Q15761 2/20 0.39
GBA1 P04062 2/20 0.38
WNT1 P04628 1/20 0.38
CYP19A1 P11511 1/20 0.38
CLK2 P49760 1/20 0.37
CLK3 P49761 1/20 0.37
DYRK1A Q13627 1/20 0.37
FGFR1 P11362 1/20 0.37
PIM1 P11309 1/20 0.37
PIM3 Q86V86 1/20 0.37
PIM2 Q9P1W9 1/20 0.37
MEN1 O00255 2/20 0.37
ALDH1A1 P00352 2/20 0.37
KMT2A Q03164 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17483449 0.99 TLR8 (0.41) TLR8TLR7TLR9CYP11B1CYP11B2
SCHEMBL17483377 0.92 TLR8 (0.40) TLR8TLR7TLR9CYP11B1CYP11B2
SCHEMBL17483434 0.92 TLR8 (0.41) TLR8TLR7TLR9CYP11B1CYP11B2
SCHEMBL17483369 0.90 KDM4E (0.41) NPY5RKDM4EHPGDHTT
SCHEMBL17483431 0.90 CYP1A2 (0.43) CYP11B1CYP11B2GBA1CYP19A1MEN1
SCHEMBL17483349 0.89 MKNK1 (0.41) TDO2NPY5RPIM1MEN1ALDH1A1
SCHEMBL17483317 0.89 NPY5R (0.39) TDO2NPY5RPIM1ALDH1A1KDM4E
SCHEMBL17483448 0.89 CYP1A2 (0.45) CYP11B1CYP11B2GBA1CYP19A1MEN1
SCHEMBL17483311 0.88 CYP1A2 (0.44) CYP11B1CYP11B2GBA1CYP19A1MEN1
SCHEMBL17483306 0.88 CYP1A2 (0.44) CYP11B1CYP11B2GBA1CYP19A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3171421-B1 ORGANIC LIGHT-EMITTING ELEMENT UNIV KYUSHU NAT UNIV CORP (JP) 2023-01-25 EP disclosed
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
EP-3706182-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kyushu University National University Corporation (JP) 2020-09-09 EP disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10600983-B2 Organic electroluminescent device comprising delayed fluorescent materials KYULUX, INC. (JP) 2020-03-24 US disclosed
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound KYULUX, INC. (JP) 2020-02-11 US disclosed
EP-2980877-B1 ORGANIC ELECTROLUMINESCENT ELEMENT KYULUX INC (JP) 2017-11-29 EP disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
EP-3171421-A1 ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2017-05-24 EP disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160308145-A1 LIGHT-EMITTING MATERIAL, AND DELAYED FLUORESCENT EMITTER AND ORGANIC LIGHT-EMITTING DEVICE USING SAME KYULUX, INC. (JP) 2016-10-20 US disclosed
US-20160308145-A1 LIGHT-EMITTING MATERIAL, AND DELAYED FLUORESCENT EMITTER AND ORGANIC LIGHT-EMITTING DEVICE USING SAME KYULUX, INC. (JP) 2016-10-20 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
EP-2980877-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Kyushu University, National University Corporation (JP) 2016-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND TERB1, TERT, TCOF1 TLR8 1167/4885TLR7 486/4885TLR9 304/4885
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound TERB1, TERT, TCOF1 TLR8 1167/4885TLR7 486/4885TLR9 304/4885
US-20160308145-A1 LIGHT-EMITTING MATERIAL, AND DELAYED FLUORESCENT EMITTER AND ORGANIC LIGHT-EMITTING DEVICE USING SAME NR2E3, CRY1, ARL1 TLR8 2928/4885TLR7 1010/4885TLR9 2232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.