Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.48 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27463798 | 0.84 | KCNA5 (0.51) | KCNA5KCNN4HTTTRPV1KDM4E | |
| SCHEMBL5608528 | 0.81 | L3MBTL1 (0.49) | KCNA5KCNN4HTTTRPV1CHRNB2 | |
| SCHEMBL17059858 | 0.81 | KCNA5 (0.46) | KCNA5KCNN4HTTTRPV1KDM4E | |
| SCHEMBL10442992 | 0.78 | CNR2 (0.44) | HTTKDM4EL3MBTL1MAPTNPSR1 | |
| SCHEMBL6834283 | 0.77 | POLB (0.51) | KCNA5KCNN4HTTTRPV1CHRNB2 | |
| SCHEMBL1432726 | 0.76 | NPSR1 (0.51) | KCNA5KCNN4HTTKDM4ECHRNB2 | |
| Hydrochloric Acid SCHEMBL6264261 | 0.76 | POLB (0.50) | KCNA5KCNN4HTTTRPV1KDM4E | |
| SCHEMBL18929879 | 0.75 | L3MBTL1 (0.46) | KCNA5KCNN4HTTTRPV1KDM4E | |
| Hydrochloric Acid SCHEMBL5379321 | 0.74 | KCNA5 (0.51) | KCNA5KCNN4HTTTRPV1KDM4E | |
| SCHEMBL10502805 | 0.73 | KCNA5 (0.41) | KCNA5KCNN4HTTTRPV1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031890-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR INHIBITION OF ROS | GRUENEBERG, Dorre A. | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031890-A1 | NOVEL METHODS, COMPOUNDS, AND COMPOSITIONS FOR INHIBITION OF ROS | ROS1, NOX4, NOX1 | KCNA5 3255/4885KCNN4 3446/4885HTT 3023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.