Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25698895 | 0.89 | BIRC2 (0.34) | HPGDKMT2ASMN1; SMN2BIRC2HTR6 | |
| SCHEMBL23139621 | 0.89 | BIRC2 (0.34) | HPGDKMT2ASMN1; SMN2BIRC2HTR6 | |
| Hydrochloric Acid SCHEMBL25337896 | 0.87 | HPGD (0.34) | HPGDKMT2ASMN1; SMN2BIRC2 | |
| Hydrochloric Acid SCHEMBL25337894 | 0.87 | HPGD (0.34) | HPGDKMT2ASMN1; SMN2BIRC2 | |
| SCHEMBL12350484 | 0.85 | HTR6 (0.36) | KMT2ABIRC2HTR6 | |
| SCHEMBL14856418 | 0.85 | HTR6 (0.36) | KMT2ABIRC2HTR6 | |
| SCHEMBL6582291 | 0.83 | HTR6 (0.39) | KMT2ABIRC2HTR6 | |
| Hydrochloric Acid SCHEMBL2237196 | 0.83 | HTR6 (0.35) | BIRC2HTR6 | |
| SCHEMBL6582294 | 0.83 | HTR6 (0.39) | KMT2ABIRC2HTR6 | |
| SCHEMBL15933081 | 0.82 | ALDH1A1 (0.42) | BIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015597-A1 | COMPOUNDS AS CDK SMALL-MOLECULE INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-02-04 | — | — | WO | disclosed |