Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 5/20 | 0.48 |
| ▸ | RORC | P51449 | 4/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | MAP2 | P11137 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25680118 | 0.85 | RORC (0.49) | MAPK11MAPK14RORCPARP1 | |
| SCHEMBL3898821 | 0.83 | PARP1 (0.48) | PLA2G7PARP1PDK2HSD17B10 | |
| SCHEMBL2467682 | 0.77 | TAS1R3 (0.50) | PARP1SLC6A2SLC6A4SLC6A3HSD17B10 | |
| SCHEMBL7571088 | 0.77 | GPBAR1 (0.50) | MAPK11MAPK14PLA2G7GPBAR1SLC6A3 | |
| Hydrochloric Acid SCHEMBL2780402 | 0.77 | RORC (0.50) | RORCPARP1CHEK2HSD17B10 | |
| SCHEMBL7068916 | 0.76 | CHEK2 (0.50) | MAPK11MAPK14PLA2G7PARP1CHEK2 | |
| SCHEMBL29854461 | 0.75 | MAPK14 (0.51) | MAPK14PARP1CHEK2HSD17B10 | |
| SCHEMBL2950525 | 0.74 | MKNK1 (0.60) | PARP1CHEK2HSD17B10 | |
| SCHEMBL3636122 | 0.73 | NR1H4 (0.56) | PARP1PDK2 | |
| SCHEMBL10592032 | 0.73 | PLA2G7 (0.47) | PLA2G7MAP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016018872-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-02-04 | — | — | WO | disclosed |