SCHEMBL17485263

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28823543	0.89	ALDH1A1 (0.45)	FBP1MAOAMAOBCHRM2CHRM1
	SCHEMBL2772413	0.87	CYP1A2 (0.53)	NFE2L2FBP1MAOAMAOBCYP1A2
	SCHEMBL2772409	0.87	CYP1A2 (0.53)	NFE2L2FBP1MAOAMAOBCYP1A2
	SCHEMBL79771	0.85	PTGS1 (0.50)	NFE2L2FBP1MAOAMAOBCYP1A2
	SCHEMBL10901883	0.85	HSD17B3 (0.52)	MAOAMAOBMAPT
	SCHEMBL79770	0.85	PTGS1 (0.50)	NFE2L2FBP1MAOAMAOBCYP1A2
	SCHEMBL27792900	0.85	LCK (0.59)	FBP1MAOAMAOBLCKCYP1A2
	SCHEMBL9871756	0.85	NFE2L2 (0.65)	NFE2L2FBP1CYP1A2NPC1
	SCHEMBL10901886	0.85	HSD17B3 (0.52)	MAOAMAOBMAPT
	SCHEMBL7294478	0.85	NFE2L2 (0.65)	NFE2L2FBP1CYP1A2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.