Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644871 | 1.00 | HTR2C (0.49) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| Ethane SCHEMBL10720474 | 0.98 | HTR2C (0.47) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| SCHEMBL29038389 | 0.92 | HTR2C (0.44) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| Formamide SCHEMBL29013842 | 0.89 | HTR2C (0.41) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| Acrylamide SCHEMBL29013882 | 0.82 | ALDH1A1 (0.40) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| SCHEMBL12640789 | 0.79 | HTR2C (0.46) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| SCHEMBL381889 | 0.77 | HTR2C (0.52) | HTR2CHTR2BALDH1A1KDM4ETP53 | |
| SCHEMBL15989633 | 0.76 | ALDH1A1 (0.56) | HIF1AEPAS1ALDH1A1HPGDKDM4E | |
| SCHEMBL11098662 | 0.76 | HTR2C (0.44) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| SCHEMBL2558890 | 0.76 | PTGS1 (0.46) | HTR2CHTR2BHIF1AEPAS1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041300-B | 2, 2-Dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117186049-A | 2, 2-dimethyl-2H chromene derivative containing sulfonamide unit, and preparation method and application thereof | 贵州大学 | 2023-12-08 | — | — | CN | claimed |
| CN-116283936-A | Substituted amino ether-containing 2, 2-dimethyl benzopyran derivative and salt or solvate thereof, preparation and application thereof, and composition | 沈阳药科大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116041300-A | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2023-05-02 | — | — | CN | claimed |
| CN-109096235-B | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2022-06-21 | — | — | CN | claimed |
| US-20220105054-A1 | ABSORPTION ENHANCER OF CINNAMIC ACID DERIVATIVE | YAMADA BEE COMPANY, INC. (JP) | 2022-04-07 | — | — | US | claimed |
| EP-1535918-B1 | PROCESS FOR PRODUCING AMINOBENZOPYRAN COMPOUND | NISSAN CHEMICAL IND LTD (JP) | 2010-11-03 | — | — | EP | claimed |
| US-7683189-B2 | Process for producing aminobenzopyran compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-03-23 | — | — | US | claimed |
| CN-100363358-C | Process for producing aminobenzopyran compound | NISSAN CHEMICAL IND LTD (JP) | 2008-01-23 | — | — | CN | claimed |
| EP-1716141-A1 | BENZOPYRAN DERIVATIVES, METHOD OF PRODUCTION AND USE THEREOF | Université de Liège (BE) | 2006-11-02 | — | — | EP | claimed |
| US-5605703-A | REDUCE TOXICITY OF DRUG WHEN ADMINISTERED BY INJECTION | LIPOTEC, S.A. (ES) | 1997-02-25 | — | — | US | claimed |
| US-5602267-A | Organometallic catalysts for epoxidizing prochiral olefins and a new class of amid-salicylidene ligands | HOECHST CELANESE (US) | 1997-02-11 | — | — | US | claimed |
| EP-0643626-A4 | CHIRAL CATALYSTS, CATALYTIC OXIDATION AND DISPROPORTIONATION REACTIONS, AND METHODS OF PRODUCING EPOXYCHROMANS AND TAXOL. | RES CORP TECHNOLOGIES INC (US) | 1995-12-06 | — | — | EP | claimed |
| EP-0643626-A1 | CHIRAL CATALYSTS, CATALYTIC OXIDATION AND DISPROPORTIONATION REACTIONS, AND METHODS OF PRODUCING EPOXYCHROMANS AND TAXOL | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-22 | — | — | EP | claimed |
| US-5391751-A | Hypotensive, antiarrhythmia, antiasthmatic agents | RED BALLOON INVESTMENT LIMITED (JE) | 1995-02-21 | — | — | US | claimed |
| EP-0312432-B1 | 2,2-Dimethyl chromene derivatives, preparation process and pharmaceutical compositions containing them | SANOFI ELF (FR) | 1994-01-12 | — | — | EP | claimed |
| EP-0521099-A4 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY | — | 1993-10-20 | — | — | EP | claimed |
| WO-1993003838-A1 | CHIRAL CATALYSTS, CATALYTIC OXIDATION AND DISPROPORTIONATION REACTIONS, AND METHODS OF PRODUCING EPOXYCHROMANS AND TAXOL | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-03-04 | — | — | WO | claimed |
| EP-0521099-A1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-01-07 | — | — | EP | claimed |
| WO-1991014694-A1 | CHIRAL CATALYSTS AND EPOXIDATION REACTIONS CATALYZED THEREBY | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1991-10-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220105054-A1 | ABSORPTION ENHANCER OF CINNAMIC ACID DERIVATIVE | FABP2, SLC16A3, SLC16A7 | HTR2C 937/4885HTR2B 515/4885HIF1A 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.