Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748567 | 1.00 | HTR2C (0.49) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| Ethane SCHEMBL10720474 | 0.98 | HTR2C (0.47) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| SCHEMBL29038389 | 0.92 | HTR2C (0.44) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| Formamide SCHEMBL29013842 | 0.89 | HTR2C (0.41) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| Acrylamide SCHEMBL29013882 | 0.82 | ALDH1A1 (0.40) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| SCHEMBL12640789 | 0.79 | HTR2C (0.46) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| SCHEMBL381889 | 0.77 | HTR2C (0.52) | HTR2CHTR2BALDH1A1KDM4ETP53 | |
| SCHEMBL15989633 | 0.76 | ALDH1A1 (0.56) | HIF1AEPAS1ALDH1A1HPGDKDM4E | |
| SCHEMBL11098662 | 0.76 | HTR2C (0.44) | HTR2CHTR2BHIF1AEPAS1ALDH1A1 | |
| SCHEMBL2558890 | 0.76 | PTGS1 (0.46) | HTR2CHTR2BHIF1AEPAS1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041300-B | 2, 2-Dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2024-04-26 | — | — | CN | claimed |
| CN-116283936-A | Substituted amino ether-containing 2, 2-dimethyl benzopyran derivative and salt or solvate thereof, preparation and application thereof, and composition | 沈阳药科大学 | 2023-06-23 | — | — | CN | claimed |
| CN-116041300-A | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2023-05-02 | — | — | CN | claimed |
| CN-109096235-B | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2022-06-21 | — | — | CN | claimed |
| CN-116041300-B | 2, 2-Dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-116041300-B | 2, 2-Dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-116041300-B | 2, 2-Dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-117756763-A | Benzopyran enantiomer and preparation method and application thereof | 云南中医药大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-116283936-A | Substituted amino ether-containing 2, 2-dimethyl benzopyran derivative and salt or solvate thereof, preparation and application thereof, and composition | 沈阳药科大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-116283936-A | Substituted amino ether-containing 2, 2-dimethyl benzopyran derivative and salt or solvate thereof, preparation and application thereof, and composition | 沈阳药科大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-116283936-A | Substituted amino ether-containing 2, 2-dimethyl benzopyran derivative and salt or solvate thereof, preparation and application thereof, and composition | 沈阳药科大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-116041300-A | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-116041300-A | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-116041300-A | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-109096235-B | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-109096235-B | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2022-06-21 | — | — | CN | disclosed |
| CN-109096235-B | 2, 2-dimethyl benzopyran derivative and preparation method and application thereof | 沈阳药科大学 | 2022-06-21 | — | — | CN | disclosed |