Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.51 |
| ▸ | LIPG | Q9Y5X9 | 11/20 | 0.41 |
| ▸ | LPL | P06858 | 10/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486143 | 0.83 | DGAT1 (0.50) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL21125909 | 0.83 | DGAT1 (0.67) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL21125910 | 0.80 | DGAT1 (0.57) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL15614859 | 0.80 | TSHR (0.48) | LIPGLPLKIF11TSHR | |
| SCHEMBL19933582 | 0.79 | DGAT1 (0.62) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL20805705 | 0.78 | DGAT1 (0.50) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL20068614 | 0.78 | DGAT1 (0.56) | DGAT1LIPGLPL | |
| SCHEMBL20805726 | 0.77 | CCR1 (0.46) | KIF11TSHRIRAK4 | |
| SCHEMBL16787665 | 0.77 | DGAT1 (0.61) | DGAT1LIPGLPLPDGFRBKDR | |
| SCHEMBL1534818 | 0.77 | LPL (0.68) | DGAT1LIPGLPLPDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174890-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-03-13 | — | — | EP | disclosed |
| US-9853228-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-26 | — | — | US | disclosed |
| US-9853228-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2017-12-26 | — | — | US | disclosed |
| US-20170250353-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-08-31 | — | — | US | disclosed |
| US-20170250353-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2017-08-31 | — | — | US | disclosed |
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170250353-A1 | METAL COMPLEXES | SOD1, AP1M1, AP3M1 | DGAT1 2063/4885LIPG 3210/4885LPL 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.