Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 9/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486108 | 0.82 | FEN1 (0.41) | FEN1ALOX5APHPGDSL3MBTL1ALDH1A1 | |
| SCHEMBL17486212 | 0.81 | MEN1 (0.34) | FEN1ALOX5APATRL3MBTL1ALDH1A1 | |
| SCHEMBL17486328 | 0.73 | PDGFRB (0.38) | L3MBTL1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL17486348 | 0.68 | MEN1 (0.35) | FEN1ALOX5APL3MBTL1ALDH1A1LMNA | |
| SCHEMBL17486341 | 0.68 | MEN1 (0.39) | HPGDSL3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL17486202 | 0.68 | RARG (0.35) | FEN1ALOX5APL3MBTL1ALDH1A1MAPT | |
| SCHEMBL17486161 | 0.67 | FEN1 (0.34) | FEN1ALOX5AP | |
| SCHEMBL20319819 | 0.66 | LMNA (0.47) | FEN1ALOX5APL3MBTL1DHODHLMNA | |
| SCHEMBL17427066 | 0.65 | PDK2 (0.35) | FEN1HPGDSL3MBTL1ALDH1A1MAPT | |
| SCHEMBL28901470 | 0.65 | NPC1 (0.45) | HPGDSL3MBTL1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |