Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 4/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486348 | 0.87 | MEN1 (0.35) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL17486212 | 0.86 | MEN1 (0.34) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL17486205 | 0.84 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL17486329 | 0.83 | RARB (0.42) | RARGRARBMEN1ALDH1A1MAPT | |
| SCHEMBL17486208 | 0.81 | MEN1 (0.34) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL17486349 | 0.81 | KDM4E (0.37) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL17486303 | 0.79 | L3MBTL1 (0.46) | RARGRARBMEN1ALDH1A1MAPT | |
| SCHEMBL17486350 | 0.77 | CYP2A6 (0.39) | MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17486307 | 0.77 | CNR2 (0.36) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL17486029 | 0.77 | RARB (0.44) | RARGRARBMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015815-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |