Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 5/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17354485 | 0.94 | IGF1R (0.36) | IGF1RHDAC1KMT2AP2RY1MEN1 | |
| SCHEMBL14850219 | 0.91 | KIT (0.36) | IGF1RHDAC1P2RY1 | |
| SCHEMBL17486581 | 0.89 | IGF1R (0.33) | IGF1RP2RY1 | |
| SCHEMBL17486543 | 0.88 | KMT2A (0.34) | IGF1RHDAC1KMT2AP2RY1MEN1 | |
| SCHEMBL17486575 | 0.88 | IGF1R (0.33) | IGF1RP2RY1 | |
| SCHEMBL17354245 | 0.88 | POLB (0.35) | HDAC1KMT2AMEN1 | |
| SCHEMBL17486553 | 0.86 | IGF1R (0.33) | IGF1RP2RY1 | |
| SCHEMBL17486568 | 0.86 | HDAC1 (0.36) | IGF1RHDAC1KMT2AP2RY1MEN1 | |
| SCHEMBL14850209 | 0.85 | KIT (0.35) | IGF1RHDAC1 | |
| SCHEMBL14850232 | 0.85 | LYN (0.32) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160031828-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | SILICON VALLEY BANK | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031828-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MPO, LPO, CAT | IGF1R 4795/4885HDAC1 2713/4885KMT2A 4518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.