Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.50 |
| ▸ | ERN1 | O75460 | 4/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1125718 | 0.89 | ALDH1A1 (0.55) | ALDH1A1L3MBTL1ERN1LMNAKDM4E | |
| SCHEMBL20892674 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TRIM24TYRTRIM33L3MBTL1 | |
| SCHEMBL13191485 | 0.87 | ALDH1A1 (0.67) | ALDH1A1TRIM24TYRTRIM33L3MBTL1 | |
| SCHEMBL8447028 | 0.86 | ALDH1A1 (0.71) | ALDH1A1TRIM24TYRTRIM33L3MBTL1 | |
| SCHEMBL702232 | 0.86 | ALDH1A1 (0.71) | ALDH1A1TRIM24TYRTRIM33L3MBTL1 | |
| SCHEMBL20488634 | 0.86 | KDM4E (0.59) | ALDH1A1TRIM24TYRTRIM33CYP1A2 | |
| SCHEMBL4623519 | 0.85 | CYP1A2 (0.54) | ALDH1A1CYP1A2CYP1A1CYP1B1CYP2C19 | |
| SCHEMBL4623521 | 0.85 | CYP1A2 (0.54) | ALDH1A1CYP1A2CYP1A1CYP1B1CYP2C19 | |
| SCHEMBL3209556 | 0.85 | ALDH1A1 (0.69) | ALDH1A1TRIM24TYRTRIM33L3MBTL1 | |
| SCHEMBL28518106 | 0.84 | ALDH1A1 (0.51) | ALDH1A1CYP1A2ERN1LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746069-A | Three-step multi-tone hair dyeing method | 汉高股份有限及两合公司 | 2022-07-12 | — | — | CN | claimed |
| CN-114173750-A | Improving the stability of agents for treating keratin materials | 汉高股份有限及两合公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113185391-A | Method for synthesizing isovanillin | 浙江优创材料科技股份有限公司 | 2021-07-30 | — | — | CN | disclosed |
| US-20200068928-A1 | METHOD FOR MODULATING THE FLAVOR PROFILE OF A FOOD | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2020-03-05 | — | — | US | disclosed |
| US-7968568-B2 | [1-(4-chloro-3-ethoxy-benzyl)-piperidin-4-yl]-(2-chloro-pyrimidin-4-yl)-amine; somatostatin receptor subtype 5 (SSTR5) antagonists; diabetes mellitus | HOFFMANN-LA ROCHE INC. (US) | 2011-06-28 | — | — | US | disclosed |
| US-20100069413-A1 | Pyrimidine and Quinazoline Derivatives | CHRIST ANDREAS D | 2010-03-18 | — | — | US | disclosed |
| US-7674804-B2 | Pyrimidine and quinazoline derivatives as SST5 modulators | HOFFMANN-LA ROCHE INC. (US) | 2010-03-09 | — | — | US | disclosed |
| EP-2155751-A1 | PYRROLOPYRIMIDIN-7-ONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | AstraZeneca AB (SE) | 2010-02-24 | — | — | EP | disclosed |
| US-20090099195-A1 | Therapeutic Compounds 570 | ASTRAZENECA AB (SE) | 2009-04-16 | — | — | US | disclosed |
| US-20090099195-A1 | Therapeutic Compounds 570 | ASTRAZENECA AB (SE) | 2009-04-16 | — | — | US | disclosed |
| US-20090099195-A1 | Therapeutic Compounds 570 | ASTRAZENECA AB (SE) | 2009-04-16 | — | — | US | disclosed |
| WO-2008136756-A1 | PYRROLOPYRIMIDIN-7-ONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | ASTRAZENECA AB (SE) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008136756-A1 | PYRROLOPYRIMIDIN-7-ONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | ASTRAZENECA AB (SE) | 2008-11-13 | — | — | WO | disclosed |
| US-20080045550-A1 | Pyrimidine and quinazoline derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2008-02-21 | — | — | US | disclosed |
| EP-1307193-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | Affymax Research Institute (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002009706-A1 | AGONISTS OF FOLLICLE STIMULATING HORMONE ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099195-A1 | Therapeutic Compounds 570 | OPRL1, OPRK1, OPRM1 | ALDH1A1 245/4885TRIM24 4558/4885TYR 329/4885 |
| US-20100069413-A1 | Pyrimidine and Quinazoline Derivatives | SSTR5, SSTR3, NPY5R | ALDH1A1 2667/4885TRIM24 4731/4885TYR 1000/4885 |
| US-20080045550-A1 | Pyrimidine and quinazoline derivatives | SSTR5, SSTR3, NPY5R | ALDH1A1 2667/4885TRIM24 4731/4885TYR 1000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.