Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17486948 | 0.87 | ENPP2 (0.79) | ENPP2 | |
| SCHEMBL17486947 | 0.86 | ENPP2 (0.60) | ENPP2 | |
| SCHEMBL17486942 | 0.81 | ENPP2 (0.54) | ENPP2 | |
| SCHEMBL17486945 | 0.80 | ENPP2 (0.46) | ENPP2 | |
| SCHEMBL26017343 | 0.76 | HRH1 (0.45) | ENPP2 | |
| SCHEMBL18597293 | 0.75 | ENPP2 (0.71) | ENPP2 | |
| SCHEMBL14892578 | 0.75 | ENPP2 (1.00) | ENPP2 | |
| SCHEMBL14892206 | 0.75 | ENPP2 (1.00) | ENPP2 | |
| SCHEMBL19271273 | 0.74 | DDB1 (0.46) | ENPP2 | |
| SCHEMBL14891065 | 0.74 | ENPP2 (1.00) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9862721-B2 | Tetrahydrocarboline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-01-09 | — | — | US | disclosed |
| US-9353113-B2 | Tetrahydrocarboline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2016-05-31 | — | — | US | disclosed |
| US-20160031884-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031884-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ENPP2, ENPP1, ACER2 | ENPP2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.