Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9615095 | 0.88 | PTGDR2 (0.62) | ENPP2PTGDR2 | |
| SCHEMBL17486943 | 0.81 | ENPP2 (0.61) | ENPP2 | |
| SCHEMBL8804790 | 0.78 | BCHE (0.56) | — | |
| SCHEMBL19132555 | 0.78 | PTGDR2 (0.66) | PTGDR2 | |
| SCHEMBL9615094 | 0.76 | PTGDR2 (0.57) | ENPP2PTGDR2 | |
| SCHEMBL23148492 | 0.75 | PTGDR2 (0.59) | PTGDR2 | |
| SCHEMBL9615138 | 0.75 | HDAC6 (0.64) | PTGDR2 | |
| SCHEMBL967543 | 0.73 | TSHR (0.52) | ENPP2PTGDR2 | |
| SCHEMBL5373029 | 0.73 | ENPP2 (0.53) | ENPP2PTGDR2 | |
| SCHEMBL14891182 | 0.73 | ENPP2 (0.79) | ENPP2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9862721-B2 | Tetrahydrocarboline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-01-09 | — | — | US | disclosed |
| US-9353113-B2 | Tetrahydrocarboline derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2016-05-31 | — | — | US | disclosed |
| US-20160031884-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031884-A1 | TETRAHYDROCARBOLINE DERIVATIVE | ENPP2, ENPP1, ACER2 | ENPP2 1/4885PTGDR2 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.