Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488014 | 0.86 | POLB (0.50) | RAB9ASMN1; SMN2TP53CYP3A4LMNA | |
| SCHEMBL18965768 | 0.82 | CYP3A4 (0.52) | RAB9ASMN1; SMN2CYP3A4SCN9ANPC1 | |
| SCHEMBL17488229 | 0.80 | KDR (0.42) | RAB9ASMN1; SMN2TP53CYP3A4CYP1A2 | |
| SCHEMBL17488151 | 0.79 | RAB9A (0.42) | RAB9ASMN1; SMN2TP53PDE10ACYP3A4 | |
| SCHEMBL17487452 | 0.79 | RAB9A (0.47) | RAB9ASMN1; SMN2TP53CYP3A4NPC1 | |
| SCHEMBL17487718 | 0.78 | RAB9A (0.43) | RAB9ASMN1; SMN2TP53CYP3A4LMNA | |
| SCHEMBL17488105 | 0.78 | RAB9A (0.41) | RAB9ASMN1; SMN2TP53PDE10ACYP3A4 | |
| SCHEMBL17488332 | 0.77 | KDR (0.40) | RAB9ASMN1; SMN2TP53PDE10ACYP3A4 | |
| SCHEMBL17487960 | 0.77 | RAB9A (0.44) | RAB9ASMN1; SMN2TP53PDE10ANPC1 | |
| SCHEMBL17487497 | 0.77 | RAB9A (0.49) | RAB9ASMN1; SMN2TP53PDE10ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |