Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488151 | 0.85 | RAB9A (0.42) | KDRRAB9ASMN1; SMN2TP53P2RX3 | |
| SCHEMBL17488256 | 0.82 | CYP3A4 (0.39) | TP53P2RX3CYP3A4LMNA | |
| SCHEMBL17488014 | 0.81 | POLB (0.50) | KDRRAB9ASMN1; SMN2TP53TEK | |
| SCHEMBL17488333 | 0.81 | KDR (0.39) | KDRRAB9ASMN1; SMN2TP53TEK | |
| SCHEMBL17487718 | 0.79 | RAB9A (0.43) | KDRRAB9ASMN1; SMN2TP53TEK | |
| SCHEMBL17487452 | 0.78 | RAB9A (0.47) | RAB9ASMN1; SMN2TP53CYP1A2CYP2D6 | |
| SCHEMBL17488143 | 0.78 | RAB9A (0.40) | KDRRAB9ASMN1; SMN2TP53CDK1 | |
| SCHEMBL17488029 | 0.78 | RAB9A (0.43) | KDRRAB9ASMN1; SMN2TP53RAF1 | |
| SCHEMBL17488016 | 0.77 | TP53 (0.41) | KDRRAB9ASMN1; SMN2TP53TEK | |
| SCHEMBL17487750 | 0.77 | P2RX3 (0.44) | KDRRAB9ASMN1; SMN2TP53TEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |