Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | TEK | Q02763 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488014 | 0.85 | POLB (0.50) | KDRTEKRAB9ATP53SMN1; SMN2 | |
| SCHEMBL17487722 | 0.80 | RAB9A (0.45) | KDRTEKRAB9ATP53SMN1; SMN2 | |
| SCHEMBL17488105 | 0.79 | RAB9A (0.41) | RAB9ATP53SMN1; SMN2CYP3A4P2RX3 | |
| SCHEMBL17488151 | 0.78 | RAB9A (0.42) | KDRRAB9ATP53SMN1; SMN2CYP3A4 | |
| SCHEMBL17487452 | 0.78 | RAB9A (0.47) | RAB9ATP53SMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL17487718 | 0.77 | RAB9A (0.43) | KDRTEKRAB9ATP53SMN1; SMN2 | |
| SCHEMBL17487483 | 0.77 | P2RX3 (0.38) | RAB9ATP53SMN1; SMN2CYP3A4P2RX3 | |
| SCHEMBL17488332 | 0.76 | KDR (0.40) | KDRTEKRAB9ATP53SMN1; SMN2 | |
| SCHEMBL17487750 | 0.76 | P2RX3 (0.44) | KDRTEKRAB9ATP53SMN1; SMN2 | |
| SCHEMBL17488016 | 0.76 | TP53 (0.41) | KDRTEKRAB9ATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |