Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18965919 | 0.82 | RAB9A (0.36) | RAB9ALMNAMEN1NPC1KMT2A | |
| SCHEMBL17487761 | 0.80 | RAB9A (0.44) | RAB9ALMNAMEN1NPC1KMT2A | |
| SCHEMBL17487326 | 0.79 | RAB9A (0.46) | RAB9ALMNAMEN1NPC1KMT2A | |
| SCHEMBL17487541 | 0.78 | RAB9A (0.39) | RAB9ALMNAMEN1NPC1KMT2A | |
| SCHEMBL17487542 | 0.77 | HTR6 (0.41) | RAB9ALMNAMEN1NPC1KMT2A | |
| SCHEMBL17487503 | 0.73 | CNR2 (0.37) | RAB9ALMNAMEN1NPC1KMT2A | |
| SCHEMBL17487676 | 0.73 | CYP3A4 (0.36) | RAB9ALMNAMEN1NPC1KMT2A | |
| SCHEMBL17488196 | 0.72 | RAB9A (0.43) | RAB9ALMNAMEN1NPC1KMT2A | |
| SCHEMBL17487996 | 0.70 | RAB9A (0.45) | RAB9ALMNAMEN1NPC1KMT2A | |
| SCHEMBL17488108 | 0.70 | RAB9A (0.43) | RAB9ALMNAMEN1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |