Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.63 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.63 |
| ▸ | TNF | P01375 | 2/20 | 0.63 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.63 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17487315 | 0.88 | SOS1 (0.59) | NOD1SOS1TNFNOD2CXCL8 | |
| SCHEMBL17487426 | 0.80 | CXCL8 (0.50) | NOD1SOS1TNFNOD2CXCL8 | |
| SCHEMBL17487454 | 0.80 | CSF1R (0.50) | NOD1SOS1TNFNOD2CXCL8 | |
| SCHEMBL17487358 | 0.79 | SOS1 (0.48) | NOD1SOS1TNFNOD2CXCL8 | |
| SCHEMBL7337702 | 0.78 | NOD1 (1.00) | NOD1SOS1TNFNOD2CXCL8 | |
| SCHEMBL17487437 | 0.78 | CSF1R (0.51) | NOD1SOS1TNFNOD2CXCL8 | |
| SCHEMBL17488183 | 0.77 | NOD1 (0.52) | NOD1SOS1TNFNOD2CXCL8 | |
| SCHEMBL18960382 | 0.76 | SOS1 (0.56) | NOD1SOS1TNFNOD2CXCL8 | |
| SCHEMBL17488006 | 0.75 | KMT2A (0.47) | NOD1SOS1TNFNOD2CXCL8 | |
| SCHEMBL17487436 | 0.75 | SOS1 (0.44) | NOD1SOS1TNFNOD2CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |