Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488029 | 0.90 | RAB9A (0.43) | RAB9ASMN1; SMN2TP53KDRLMNA | |
| SCHEMBL17488145 | 0.86 | RAB9A (0.41) | RAB9ASMN1; SMN2TP53KDRLMNA | |
| SCHEMBL17488153 | 0.85 | RAB9A (0.43) | RAB9ASMN1; SMN2TP53KDRLMNA | |
| SCHEMBL17488028 | 0.83 | PLK4 (0.41) | RAB9ASMN1; SMN2TP53KDRHTT | |
| SCHEMBL17487497 | 0.80 | RAB9A (0.49) | RAB9ASMN1; SMN2TP53KDRLMNA | |
| SCHEMBL17487821 | 0.78 | RAB9A (0.43) | RAB9ASMN1; SMN2TP53KDRLMNA | |
| SCHEMBL17488332 | 0.78 | KDR (0.40) | RAB9ASMN1; SMN2TP53KDRLMNA | |
| SCHEMBL17488038 | 0.78 | KDR (0.42) | RAB9ASMN1; SMN2TP53KDRLMNA | |
| SCHEMBL17488037 | 0.78 | KDR (0.40) | RAB9ASMN1; SMN2TP53KDRLMNA | |
| SCHEMBL17488333 | 0.78 | KDR (0.39) | RAB9ASMN1; SMN2TP53KDRRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |