Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488158 | 0.92 | RIPK1 (0.35) | RAF1RIPK1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL17487996 | 0.88 | RAB9A (0.45) | RAF1RIPK1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL17488124 | 0.86 | RAB9A (0.42) | RAF1RAB9AKDRTP53SMN1; SMN2 | |
| SCHEMBL17488013 | 0.84 | RAB9A (0.39) | RAF1RIPK1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL17488237 | 0.84 | RAB9A (0.40) | RIPK1RAB9ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17488105 | 0.83 | RAB9A (0.41) | RAF1RIPK1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL17488096 | 0.82 | RAB9A (0.42) | RAF1RIPK1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL17488033 | 0.81 | RAB9A (0.42) | RAF1RIPK1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL17487495 | 0.81 | RAB9A (0.42) | RAB9ATP53SMN1; SMN2CSNK1A1CSNK1D | |
| SCHEMBL17487716 | 0.81 | SMN1; SMN2 (0.43) | RAF1RIPK1RAB9ACYP2C9KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |