Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | IL6 | P05231 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488105 | 0.95 | RAB9A (0.41) | RAB9ASMN1; SMN2TP53P2RX3RIPK1 | |
| SCHEMBL17488011 | 0.93 | RIPK1 (0.37) | RAB9ASMN1; SMN2TP53RIPK1DGAT1 | |
| SCHEMBL17487996 | 0.90 | RAB9A (0.45) | RAB9ASMN1; SMN2TP53RIPK1CYP1A2 | |
| SCHEMBL17487676 | 0.88 | CYP3A4 (0.36) | RAB9ASMN1; SMN2TP53P2RX3IL6 | |
| SCHEMBL17488240 | 0.88 | RAB9A (0.41) | RAB9ASMN1; SMN2TP53IL6TLR7 | |
| SCHEMBL17488159 | 0.88 | RAB9A (0.41) | RAB9ASMN1; SMN2TP53P2RX3IL6 | |
| SCHEMBL17487820 | 0.88 | RAB9A (0.39) | RAB9ASMN1; SMN2TP53RIPK1CYP1A2 | |
| SCHEMBL17488158 | 0.87 | RIPK1 (0.35) | RAB9ASMN1; SMN2TP53RIPK1IL6 | |
| SCHEMBL17488096 | 0.86 | RAB9A (0.42) | RAB9ASMN1; SMN2TP53RIPK1CYP1A2 | |
| SCHEMBL17488103 | 0.86 | SCN9A (0.47) | RAB9ASMN1; SMN2TP53KCNH2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |